Fmoc-4-fluoro-L-phenylglycine (Fmoc-4-fluoro-L-phenylglycine) is an organic compound, mainly used for solid phase synthesis and peptide synthesis of probes and functional molecules. The following is a description of the nature, use, preparation and safety information of the substance:
Nature:
-Molecular formula: C21H17FNO4
-Molecular weight: 375.36g/mol
-Appearance: White or off-white solid
-melting point: about 170-175 ℃
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO), dichloromethane and alcohol, insoluble in water
Use:
- Fmoc-4-fluoro-L-phenylglycine is an important amino acid derivative commonly used in solid-phase synthesis and peptide synthesis.
-It can be used as a component of the peptide chain to construct peptides with specific structure and function by connecting with other amino acids.
- Fmoc-4-fluoro-L-phenylglycine can also be used in drug development, protein engineering and other fields.
Preparation Method:
The preparation of Fmoc-4-fluoro-L-phenylglycine is generally accomplished by organic synthesis methods. The specific synthetic route is complex, involving a series of reactions and steps, which need to be carried out under controlled conditions to ensure yield and purity.
Safety Information:
-The Fmoc-4-fluoro-L-phenylglycine is non-toxic to humans under normal operating conditions.
-Due to the characteristics of its organic compounds, care should be taken to avoid direct contact with skin, eyes and inhalation of its dust. Wear appropriate protective equipment such as laboratory gloves, goggles and masks when used.
-In the event of aspiration or contact, flush the affected area immediately with plenty of water and seek medical attention.